Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20334488 | 0.76 | — | — | |
| SCHEMBL24862909 | 0.71 | NOS1 (0.41) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL24520374 | 0.68 | — | — | |
| SCHEMBL25101526 | 0.68 | NOS1 (0.38) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL910154 | 0.68 | — | — | |
| SCHEMBL18828488 | 0.68 | — | — | |
| SCHEMBL16411466 | 0.67 | — | — | |
| SCHEMBL24146631 | 0.66 | NOS1 (0.32) | NOS1NOS2 | |
| Hydrogen Sulfide SCHEMBL5678855 | 0.66 | — | — | |
| SCHEMBL20936643 | 0.65 | CA1 (0.35) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118627-A1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | SAREPTA THERAPEUTICS, INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018118662-A1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | SAREPTA THERAPEUTICS, INC. (US) | 2018-06-28 | — | — | WO | disclosed |