Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | NOS2 | P35228 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18748368 | 0.79 | CA1 (0.37) | NOS1NOS2CA1CA2CA4 | |
| SCHEMBL26728970 | 0.78 | NOS3 (0.31) | NOS1NOS2NOS3 | |
| SCHEMBL25101526 | 0.77 | NOS1 (0.38) | NOS1NOS2NOS3CA1CA2 | |
| SCHEMBL760020 | 0.76 | — | — | |
| SCHEMBL14616020 | 0.76 | — | — | |
| SCHEMBL13063337 | 0.76 | — | — | |
| SCHEMBL23547706 | 0.74 | NOS1 (0.39) | NOS1NOS2NOS3CA1CA2 | |
| SCHEMBL22773011 | 0.73 | GABRR1 (0.30) | — | |
| SCHEMBL17128770 | 0.73 | DPP4 (0.35) | NOS1NOS2NOS3 | |
| SCHEMBL23252982 | 0.71 | CA1 (0.37) | NOS1NOS2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4122497-A1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | Sarepta Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-4115908-A1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | Sarepta Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |