Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285229 | 0.81 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL27466670 | 0.79 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL13826574 | 0.78 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL27485630 | 0.78 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL12182227 | 0.76 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL9114515 | 0.76 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL12825487 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL19559100 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL25156142 | 0.74 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL23616938 | 0.73 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018112843-A1 | HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |