SCHEMBL285229

SCHEMBL285229

C=C(C=C(C)C(=O)O)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
CYP2C9 P11712 1/20 0.33
MAPT P10636 3/20 0.32
APEX1 P27695 2/20 0.31
KDM4E B2RXH2 1/20 0.31
EGLN1 Q9GZT9 1/20 0.30
LMNA P02545 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27466670 0.98 ALDH1A1 (0.44) ALDH1A1CYP2C9MAPTAPEX1KDM4E
SCHEMBL9114515 0.94 ALDH1A1 (0.58) ALDH1A1CYP2C9
Acrylonitrile SCHEMBL6554745 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL4947083 0.86 ALDH1A1 (0.58) ALDH1A1CYP2C9
SCHEMBL10449919 0.85 ALDH1A1 (0.42) ALDH1A1MAPTEGLN1LMNANPSR1
Phthalic Acid SCHEMBL16932936 0.83 ALDH1A1 (0.42) ALDH1A1CYP2C9APEX1KDM4ELMNA
SCHEMBL23088631 0.83 ALDH1A1 (0.46) ALDH1A1MAPTKDM4EEGLN1
Acrylic Acid Ethyl Ester SCHEMBL9067599 0.82 NPSR1 (0.38) ALDH1A1NPSR1
SCHEMBL195064 0.81 ALDH1A1 (0.47) ALDH1A1MAPTEGLN1LMNANPSR1
SCHEMBL11696200 0.81 CTH (0.33) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240180978-A1 PREPARATIONS COMPRISING PROBIOTIC STRAINS AND L-TRYPTOPHAN EVONIK OPERATIONS GMBH (DE) 2024-06-06 US claimed
WO-2024119044-A2 ADRULIPASE COMPOSITIONS First Wave BioPharma, Inc. (US) 2024-06-06 WO claimed
US-20240156882-A1 PREPARATIONS COMPRISING PROBIOTIC STRAINS AND ANTHOCYANINS EVONIK OPERATIONS GMBH (DE) 2024-05-16 US claimed
US-11975103-B2 Compositions of midodrine and methods of using the same XENAMED CORP. (US) 2024-05-07 US claimed
EP-4301385-A1 PREPARATIONS COMPRISING PROBIOTIC STRAINS AND ANTHOCYANINS Evonik Operations GmbH (DE) 2024-01-10 EP claimed
EP-4301163-A1 PREPARATIONS COMPRISING PROBIOTIC STRAINS AND L-TRYPTOPHAN Evonik Operations GmbH (DE) 2024-01-10 EP claimed
CN-114126590-B Pharmaceutical preparation and method for producing the same 富士制药工业股份有限公司 2024-01-05 CN claimed
US-20230398173-A1 Delayed Release Compositions of Linaclotide IRONWOOD PHARMACEUTICALS INC (US) 2023-12-14 US claimed
WO-2023213584-A1 A METHOD OF CELL REJUVENATION EVONIK OPERATIONS GMBH (DE) 2023-11-09 WO claimed
CN-116942565-A Dispersion liquid and preparation method and application thereof 宁波爱诗化妆品有限公司 2023-10-27 CN claimed
WO-2008065502-A1 PHARMACEUTICAL COMPOSITIONS BASED ON A) NANOPARTICLES COMPRISING ENTERIC POLYMERS AND B) CASEIN PFIZER PRODUCTS INC. (US) 2008-06-05 WO claimed
WO-2008065506-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING NANOPARTICLES COMPRISING ENTERIC POLYMERS AND CASEIN PFIZER PRODUCTS INC. (US) 2008-06-05 WO claimed
CN-101190401-A Hydrophilic polyvinylidene fluoride hollow fiber microporous membrane and preparation method thereof HAINAN LISHENG WATER PURIFICAT (CN) 2008-06-04 CN claimed
WO-2007127630-A1 CONTROLLED RELEASED PREPARATIONS OF OXCARBAZEPINE HAVING SIGMOIDAL RELEASE PROFILE SUPERNUS PHARMACEUTICALS, INC (US) 2007-11-08 WO claimed
CN-101066525-A Process of preparing micron level ordered porous aza titania microsphere UNIV WUHAN ENGINEERING (CN) 2007-11-07 CN claimed
US-20070254033-A1 comprise solubility-and/or release enhancing agents to provide tailored drug release profiles, preferably sigmoidal release profiles; controlled-release preparations of oxcarbazepine and derivatives thereof for once-a-day administration SUPERNUS PHARMACEUTICALS, INC. 2007-11-01 US claimed
CN-1730116-A Conduct assembly and injection molding technological process and making equipment thereof BECTON DICKINSON CO (US) 2006-02-08 CN claimed
US-20040220250-A1 Novel oral dosage form for carvedilol Boehringer Mannhein Pharmaceutical Corporation 2004-11-04 US claimed
US-5431920-A Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents MERCK FROSST, CANADA, INC. (CA) 1995-07-11 US claimed
US-4497847-A MONO AND DIESTERS OF GLYCEROL AND SATURATED CARBOXYLIC ACIDS AS PLASTICIZERS SANKYO COMPANY, LIMITED (JP) 1985-02-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398173-A1 Delayed Release Compositions of Linaclotide LPXN, LHCGR, BRS3 ALDH1A1 3926/4885CYP2C9 1966/4885MAPT 3995/4885
US-11975103-B2 Compositions of midodrine and methods of using the same PDE3A, PDE5A, PDE3B ALDH1A1 3934/4885CYP2C9 168/4885MAPT 2275/4885
US-20040220250-A1 Novel oral dosage form for carvedilol ADRB1, ADRB2, ADRB3 ALDH1A1 929/4885CYP2C9 63/4885MAPT 2244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.