Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25763089 | 0.83 | ACACB (0.39) | MGLLSLC6A2SLC6A4DRD2ACACB | |
| SCHEMBL6296853 | 0.81 | PPARG (0.58) | MGLLMCHR1FFAR1 | |
| SCHEMBL25293176 | 0.81 | CNR1 (0.39) | MGLLMCHR1DRD2 | |
| SCHEMBL25077376 | 0.81 | CNR1 (0.39) | MGLLMCHR1DRD2 | |
| SCHEMBL6297017 | 0.79 | PDCD1 (0.46) | MGLLMCHR1PDCD1CD274FFAR1 | |
| SCHEMBL757193 | 0.78 | MGLL (0.54) | MGLLSLC6A2SLC6A4SLC6A3ACACB | |
| SCHEMBL25763036 | 0.77 | KDM4E (0.41) | MGLLSLC6A2SLC6A4 | |
| SCHEMBL509995 | 0.75 | MGLL (0.46) | MGLLMCHR1PDCD1CD274FFAR1 | |
| SCHEMBL24304936 | 0.75 | PLA2G4B (0.40) | — | |
| SCHEMBL21239928 | 0.75 | SLC6A4 (0.49) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018112843-A1 | HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |