Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23431330 | 0.86 | L3MBTL1 (0.39) | ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL19775161 | 0.83 | KDM4E (0.40) | ALDH1A1CYP2C19HIF1ASLC6A2SLC6A3 | |
| SCHEMBL24022952 | 0.83 | TSHR (0.37) | ALDH1A1CYP2C19HIF1ATDP1SLC6A2 | |
| SCHEMBL24201120 | 0.80 | CYP2C19 (0.42) | ALDH1A1CYP2C19HIF1AKMT2AL3MBTL1 | |
| SCHEMBL19775181 | 0.80 | TSHR (0.41) | ALDH1A1TDP1SLC6A2TSHRMAPK1 | |
| SCHEMBL29191654 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1SLC6A2SLC6A3KMT2A | |
| SCHEMBL19825428 | 0.79 | KDM4E (0.37) | ALDH1A1TSHRLMNA | |
| SCHEMBL21327698 | 0.78 | TSHR (0.48) | ALDH1A1TDP1SLC6A2TSHRMAPK1 | |
| SCHEMBL22170228 | 0.77 | TDP1 (0.40) | ALDH1A1TDP1TSHRMAPK1L3MBTL1 | |
| SCHEMBL12111482 | 0.76 | PPARG (0.47) | ALDH1A1CYP2C19L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018119441-A1 | EGFR PROTEOLYSIS TARGETING CHIMERIC MOLECULES AND ASSOCIATED METHODS OF USE | Arvinas, Inc. (US) | 2018-06-28 | — | — | WO | disclosed |