Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540039 | 0.94 | POLB (0.49) | POLBTERTSTING1 | |
| SCHEMBL20325289 | 0.93 | POLB (0.45) | POLBTERTSTING1ENPP1P2RY1 | |
| SCHEMBL22434625 | 0.92 | POLB (0.62) | POLBTERTP2RY2P2RY4P2RY6 | |
| SCHEMBL20324893 | 0.92 | POLB (0.49) | POLBTERTSTING1P2RY2P2RY4 | |
| SCHEMBL21133334 | 0.91 | POLB (0.49) | POLBSTING1P2RY2ENPP1P2RY1 | |
| SCHEMBL21133327 | 0.91 | POLB (0.49) | POLBSTING1P2RY2ENPP1P2RY1 | |
| SCHEMBL21132939 | 0.91 | POLB (0.49) | POLBSTING1P2RY2ENPP1P2RY1 | |
| SCHEMBL20325358 | 0.91 | STING1 (0.49) | POLBSTING1 | |
| SCHEMBL20326953 | 0.91 | STING1 (0.49) | POLBSTING1 | |
| SCHEMBL22434567 | 0.90 | POLB (0.51) | POLBTERTSTING1P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |