SCHEMBL22434625

SCHEMBL22434625

Nc1nc2c(ncn2[C@H]2C[C@H](O)[C@@H](COP(=O)(S)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(O)S)O2)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.62
▸ ENPP1 P22413 3/20 0.55
▸ P2RY1 P47900 1/20 0.55
▸ TERT O14746 1/20 0.54
▸ P2RY2 P41231 1/20 0.54
▸ P2RY4 P51582 1/20 0.54
▸ P2RY6 Q15077 1/20 0.54
▸ DTYMK P23919 4/20 0.52
▸ NT5E P21589 1/20 0.49
▸ F2 P00734 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13326140 0.94 POLB (0.60) POLBENPP1P2RY1TERTP2RY2
SCHEMBL14389942 0.94 POLB (0.60) POLBENPP1P2RY1TERTP2RY2
SCHEMBL14389876 0.94 POLB (0.61) POLBENPP1P2RY1TERTP2RY2
SCHEMBL13359725 0.94 POLB (0.61) POLBENPP1P2RY1TERTP2RY2
SCHEMBL20326933 0.92 POLB (0.52) POLBENPP1P2RY1TERTP2RY2
SCHEMBL20326935 0.91 POLB (0.51) POLBENPP1P2RY1TERTP2RY2
SCHEMBL22434567 0.91 POLB (0.51) POLBENPP1P2RY1TERTP2RY2
SCHEMBL16221597 0.91 POLB (0.51) POLBENPP1P2RY1TERTP2RY2
SCHEMBL24276631 0.90 POLB (0.54) POLBENPP1P2RY1TERTP2RY2
SCHEMBL24276647 0.90 POLB (0.54) POLBENPP1P2RY1TERTP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200291096-A1 BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF Bicyclerd Limited (GB) 2020-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200291096-A1 BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF STING1, BID, VIP POLB 2971/4885ENPP1 2025/4885P2RY1 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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