Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.48 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22524078 | 0.92 | POLB (0.47) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL20782763 | 0.92 | POLB (0.58) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL21540009 | 0.90 | TERT (0.53) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL20782764 | 0.90 | TERT (0.53) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL20325223 | 0.90 | TERT (0.53) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL20324868 | 0.90 | TERT (0.53) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL22524098 | 0.88 | POLB (0.47) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL20324811 | 0.88 | POLB (0.52) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL23679395 | 0.88 | POLB (0.49) | POLBP2RY2P2RY4P2RY6FUT5 | |
| SCHEMBL22765945 | 0.85 | TERT (0.48) | POLBP2RY2P2RY4P2RY6FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |