Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT5 | Q11128 | 1/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 9/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 2/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21942777 | 0.90 | RNASEL (0.55) | RNASELTGM2 | |
| SCHEMBL20325280 | 0.89 | FUT5 (0.52) | FUT5STING1F2RNASELTGM2 | |
| SCHEMBL22399487 | 0.87 | FUT5 (0.50) | FUT5RNASEL | |
| SCHEMBL21943904 | 0.86 | FUT5 (0.52) | FUT5RNASEL | |
| SCHEMBL20325235 | 0.86 | FUT5 (0.54) | FUT5STING1F2RNASELTGM2 | |
| SCHEMBL21454979 | 0.85 | FUT5 (0.55) | FUT5F2RNASELTGM2NT5E | |
| SCHEMBL21454748 | 0.85 | FUT5 (0.55) | FUT5F2RNASELTGM2NT5E | |
| SCHEMBL20326944 | 0.84 | FUT5 (0.48) | FUT5STING1F2RNASELTGM2 | |
| SCHEMBL22399209 | 0.84 | RNASEL (0.55) | RNASEL | |
| SCHEMBL22326689 | 0.83 | FUT5 (0.66) | FUT5RNASELTGM2NT5EDTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118665-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS FOR CANCER TREATMENT | MERCK SHARP & DOHME CORP. (US) | 2018-06-28 | — | — | WO | disclosed |