Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18342467 | 0.98 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL18342469 | 0.98 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| Trifluoroacetic Acid SCHEMBL18342384 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| Trifluoroacetic Acid SCHEMBL20479843 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL28537216 | 0.89 | MEN1 (0.50) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL7996489 | 0.83 | LMNA (0.51) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL3386010 | 0.83 | MEN1 (0.47) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL20479842 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL4253478 | 0.78 | CSNK1E (0.51) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL28542350 | 0.78 | DPP7 (0.47) | MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088788-B2 | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-03 | — | — | US | disclosed |