Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31127843 | 0.82 | SIGMAR1 (0.63) | L3MBTL1SIGMAR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL536907 | 0.82 | SIGMAR1 (0.63) | L3MBTL1SIGMAR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2852187 | 0.77 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4849306 | 0.77 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4855673 | 0.77 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL172531 | 0.77 | SIGMAR1 (0.66) | SIGMAR1SMN1; SMN2MAPTBCHEATM | |
| SCHEMBL10451642 | 0.77 | BCHE (0.71) | L3MBTL1SIGMAR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11096038 | 0.77 | BCHE (0.71) | L3MBTL1SIGMAR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9273603 | 0.76 | SIGMAR1 (0.51) | L3MBTL1SIGMAR1KMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9202671 | 0.76 | SIGMAR1 (0.51) | L3MBTL1SIGMAR1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088788-B2 | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-03 | — | — | US | disclosed |