Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14816157 | 0.82 | GPR119 (0.35) | HRH3NAAA | |
| SCHEMBL15462541 | 0.82 | GPR119 (0.35) | HRH3NAAA | |
| SCHEMBL15806356 | 0.82 | HRH3 (0.31) | HRH3 | |
| SCHEMBL14815350 | 0.81 | HRH3 (0.38) | HRH3 | |
| SCHEMBL14814818 | 0.81 | HRH3 (0.36) | HRH3 | |
| SCHEMBL14815875 | 0.79 | HTR2C (0.32) | HRH3NAAA | |
| SCHEMBL14815440 | 0.79 | HTR2C (0.32) | HRH3NAAA | |
| SCHEMBL15462416 | 0.79 | NAAA (0.40) | NAAA | |
| SCHEMBL15462445 | 0.79 | CNR1 (0.37) | NAAA | |
| SCHEMBL14815545 | 0.79 | SMN1; SMN2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118101-A1 | T-TYPE CALCIUM CHANNEL MODULATORS AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2018-06-28 | — | — | WO | disclosed |