Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624015 | 0.71 | CES1 (0.43) | GCKALDH1A1GAANPSR1TSHR | |
| SCHEMBL13574907 | 0.70 | MEN1 (0.51) | ALDH1A1GAATP53MEN1KMT2A | |
| SCHEMBL13394194 | 0.66 | ALDH1A1 (0.53) | ALDH1A1GAANPSR1TSHRLMNA | |
| SCHEMBL12601431 | 0.66 | CYP1B1 (0.47) | ALDH1A1GAANPSR1TSHRLMNA | |
| SCHEMBL19370684 | 0.65 | TP53 (0.49) | ALDH1A1GAANPSR1LMNAHTT | |
| SCHEMBL18366044 | 0.63 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTTTP53 | |
| SCHEMBL22698792 | 0.63 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTTTP53 | |
| SCHEMBL30587617 | 0.63 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTTTP53 | |
| SCHEMBL19658556 | 0.63 | ALDH1A1 (0.47) | ALDH1A1GAALMNAHTTTP53 | |
| SCHEMBL10391180 | 0.62 | ALDH1A1 (0.55) | GCKALDH1A1GAANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018118947-A1 | THIENOPYRROLE DERIVATIVES FOR USE IN TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | BIOTHERYX, INC. (US) | 2018-06-28 | — | — | WO | disclosed |