Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14629574 | 0.86 | TNF (0.42) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL19451332 | 0.86 | TNF (0.42) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL25031536 | 0.86 | GAA (0.40) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL21759891 | 0.86 | GAA (0.45) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL19370684 | 0.86 | TP53 (0.49) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL25816955 | 0.85 | MAPT (0.39) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL24267204 | 0.85 | L3MBTL1 (0.39) | ALDH1A1TP53KDM4ECYP2D6HPGD | |
| SCHEMBL22434633 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL22317736 | 0.85 | TNF (0.42) | ALDH1A1TP53POLBKDM4EGLA | |
| SCHEMBL25478328 | 0.85 | MAPK1 (0.38) | ALDH1A1TP53POLBKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236797-A1 | VARIANT CD58 DOMAINS AND USES THEREOF | NOVARTIS AG (CH) | 2020-11-26 | — | — | WO | disclosed |