Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033045 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL12585937 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL12514917 | 0.89 | GAA (0.33) | ALDH1A1KDM4ESMN1; SMN2GAARAB9A | |
| SCHEMBL12585943 | 0.88 | MAPT (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL16304014 | 0.88 | MAPT (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL2031951 | 0.87 | KDM4E (0.33) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL12585920 | 0.87 | KDM4E (0.33) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL2031950 | 0.87 | KDM4E (0.33) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL13529617 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2GAA | |
| SCHEMBL12515060 | 0.81 | MAPT (0.37) | ALDH1A1KDM4ESMN1; SMN2GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912207-B2 | 2-aldoximino-5-fluoropyrimidine derivatives | Dow AgroSciences, LLP. (US) | 2014-12-16 | — | — | US | disclosed |
| WO-2011084611-A1 | 2-ALDOXIMINO-5-FLUOROPYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20110152300-A1 | 2-ALDOXIMINO-5-FLUOROPYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152300-A1 | 2-ALDOXIMINO-5-FLUOROPYRIMIDINE DERIVATIVES | AKR7A2, DPYD, DPM1 | ALDH1A1 25/4885KDM4E 1647/4885HPGD 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.