Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12585920 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL2031951 | 1.00 | KDM4E (0.33) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL12514917 | 0.89 | GAA (0.33) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL16304014 | 0.88 | MAPT (0.38) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL12585943 | 0.88 | MAPT (0.38) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL2033047 | 0.87 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL2033045 | 0.87 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL12585937 | 0.87 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL12515461 | 0.84 | L3MBTL1 (0.35) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL12514910 | 0.83 | NFE2L2 (0.36) | KDM4EALDH1A1GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912207-B2 | 2-aldoximino-5-fluoropyrimidine derivatives | Dow AgroSciences, LLP. (US) | 2014-12-16 | — | — | US | disclosed |
| EP-2512482-A1 | 2-ALDOXIMINO-5-FLUOROPYRIMIDINE DERIVATIVES | Dow AgroSciences LLC (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084611-A1 | 2-ALDOXIMINO-5-FLUOROPYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20110152300-A1 | 2-ALDOXIMINO-5-FLUOROPYRIMIDINE DERIVATIVES | DOW AGROSCIENCES LLC | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152300-A1 | 2-ALDOXIMINO-5-FLUOROPYRIMIDINE DERIVATIVES | AKR7A2, DPYD, DPM1 | KDM4E 1647/4885ALDH1A1 25/4885GLA 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.