Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20331966 | 0.95 | TTK (0.37) | TTKPDE9A | |
| SCHEMBL21240135 | 0.95 | PDE9A (0.34) | TTKPDE9A | |
| SCHEMBL29577336 | 0.95 | PDE9A (0.34) | TTKPDE9A | |
| SCHEMBL21240326 | 0.90 | TTK (0.37) | TTKPDE9A | |
| SCHEMBL29577295 | 0.90 | TTK (0.37) | TTKPDE9A | |
| SCHEMBL21252374 | 0.89 | PDE10A (0.35) | TTK | |
| SCHEMBL20331785 | 0.89 | TTK (0.35) | TTK | |
| SCHEMBL21252442 | 0.88 | TTK (0.34) | TTK | |
| SCHEMBL20331101 | 0.87 | MEN1 (0.36) | — | |
| SCHEMBL20331761 | 0.86 | TTK (0.41) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018113584-A1 | FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 上海和誉生物医药科技有限公司 | 2018-06-28 | — | — | WO | disclosed |