SCHEMBL20331101 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	NOS1	P29475	2/20	0.34

▸	PDE4B	Q07343	5/20	0.33

▸	PDE4A	P27815	2/20	0.33

▸	PDE4C	Q08493	2/20	0.33

▸	PDE4D	Q08499	2/20	0.33

▸	PDE11A	Q9HCR9	2/20	0.33

▸	TP53	P04637	1/20	0.33

▸	PDE3B	Q13370	1/20	0.33

▸	FGFR4	P22455	3/20	0.33

▸	ALDH1A1	P00352	1/20	0.32

▸	SMN1; SMN2	Q16637	1/20	0.32

▸	CHRM4	P08173	2/20	0.31

▸	HASPIN	Q8TF76	1/20	0.30

▸	SUV39H2	Q9H5I1	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21240537	0.94	NOS1 (0.36)	MEN1KMT2ANOS1PDE4BPDE4A
SCHEMBL29578158	0.94	NOS1 (0.36)	MEN1KMT2ANOS1PDE4BPDE4A
SCHEMBL21252148	0.93	MEN1 (0.39)	MEN1KMT2ANOS1PDE4BPDE4A
SCHEMBL20331789	0.92	NOS1 (0.38)	MEN1KMT2ANOS1PDE4BPDE4A
SCHEMBL30045100	0.92	NOS1 (0.38)	MEN1KMT2ANOS1PDE4BPDE4A
SCHEMBL20331796	0.91	NOS1 (0.40)	MEN1KMT2ANOS1PDE4BPDE4A
SCHEMBL21252374	0.89	PDE10A (0.35)	MEN1KMT2APDE4BPDE4APDE4C
SCHEMBL20331785	0.89	TTK (0.35)	PDE4BPDE4APDE4CPDE4DPDE11A
SCHEMBL21252146	0.89	TTK (0.37)	PDE4BPDE4APDE4CPDE4DPDE11A
SCHEMBL21252147	0.87	MEN1 (0.36)	MEN1KMT2ANOS1PDE4BPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018113584-A1	FGFR4 INHIBITOR, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF	上海和誉生物医药科技有限公司	2018-06-28	—	—	WO	disclosed