Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20317591 | 0.77 | ALOX5 (0.37) | ALOX5DGAT1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12207216 | 0.75 | DGAT1 (0.41) | ALOX5DGAT1HSP90AB1 | |
| SCHEMBL19452281 | 0.72 | MAPT (0.46) | MMP8 | |
| SCHEMBL12392763 | 0.70 | NPC1 (0.42) | ALOX5DGAT1NPC1MMP2MMP9 | |
| SCHEMBL18792791 | 0.70 | DGAT1 (0.41) | DGAT1CTSLCTSSCTSKNPC1 | |
| SCHEMBL12840969 | 0.69 | CYP1A2 (0.38) | ALOX5DGAT1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17404786 | 0.68 | DGAT1 (0.40) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL21099982 | 0.68 | DGAT1 (0.42) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL21117940 | 0.68 | DGAT1 (0.55) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL25911678 | 0.68 | DGAT1 (0.40) | ALOX5DGAT1HSP90AB1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018119053-A1 | ARRAYS INCLUDING A RESIN FILM AND A PATTERNED POLYMER LAYER | ILLUMINA, INC. (US) | 2018-06-28 | — | — | WO | disclosed |