Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487339 | 0.86 | MEN1 (0.57) | SORT1NPC1RAB9AKMT2AGAA | |
| SCHEMBL20610223 | 0.84 | SORT1 (0.68) | SORT1NPC1RAB9AKMT2AGAA | |
| SCHEMBL29980979 | 0.83 | SORT1 (1.00) | SORT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL15903084 | 0.83 | SORT1 (1.00) | SORT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL15903086 | 0.83 | SORT1 (0.90) | SORT1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1818730 | 0.83 | SORT1 (0.67) | SORT1NPC1RAB9AKMT2AGAA | |
| SCHEMBL30417260 | 0.83 | SORT1 (0.67) | SORT1NPC1RAB9AKMT2AGAA | |
| SCHEMBL14636633 | 0.82 | MEN1 (0.69) | NPC1RAB9AKMT2AGAASMN1; SMN2 | |
| SCHEMBL30362638 | 0.82 | MEN1 (0.69) | NPC1RAB9AKMT2AGAASMN1; SMN2 | |
| SCHEMBL3846118 | 0.81 | SORT1 (0.73) | SORT1NPC1RAB9AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858833-B9 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREOF AND USE THEREOF | TRANSTHERA SCIENCES NANJING INC (CN) | 2026-03-11 | — | — | EP | disclosed |
| EP-3858833-B1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREOF AND USE THEREOF | TRANSTHERA SCIENCES NANJING INC (CN) | 2025-10-22 | — | — | EP | disclosed |
| US-12291534-B2 | Aminonorbornane derivative and manufacture method therefor and use thereof | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2025-05-06 | — | — | US | disclosed |
| US-11420975-B2 | Substituted imidazo[1,5-a]pyrazines as Bruton's tyrosine kinase inhibitors | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2022-08-23 | — | — | US | disclosed |
| US-20220144843-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2022-05-12 | — | — | US | disclosed |
| US-20220144843-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2022-05-12 | — | — | US | disclosed |
| US-20210332057-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2021-10-28 | — | — | US | disclosed |
| US-20210332057-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2021-10-28 | — | — | US | disclosed |
| EP-3858833-A1 | AMINONORDECANE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858833-A1 | AMINONORDECANE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| WO-2020063012-A1 | AMINONORDECANE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京亘泰医药技术有限公司 | 2020-04-02 | — | — | WO | disclosed |
| WO-2020063012-A1 | AMINONORDECANE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京亘泰医药技术有限公司 | 2020-04-02 | — | — | WO | disclosed |
| WO-2019056466-A1 | BRUTON TYROSINE KINASE INHIBITOR | 南京亘泰医药技术有限公司 | 2019-03-28 | — | — | WO | disclosed |
| WO-2018113085-A1 | BRUTON'S TYROSINE KINASE INHIBITOR | 南京亘泰医药技术有限公司 | 2018-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291534-B2 | Aminonorbornane derivative and manufacture method therefor and use thereof | BTK, LCK, SYK | SORT1 2926/4885NPC1 3453/4885RAB9A 1752/4885 |
| US-11420975-B2 | Substituted imidazo[1,5-a]pyrazines as Bruton's tyrosine kinase inhibitors | BTK, SYK, LCK | SORT1 4598/4885NPC1 3937/4885RAB9A 1111/4885 |
| US-20210332057-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | BTK, LCK, SYK | SORT1 2926/4885NPC1 3453/4885RAB9A 1752/4885 |
| US-20220144843-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | BTK, LCK, SYK | SORT1 2926/4885NPC1 3453/4885RAB9A 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.