Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOX18 | P35713 | 1/20 | 1.00 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.58 |
| ▸ | EP300 | Q09472 | 2/20 | 0.58 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.58 |
| ▸ | BID | P55957 | 4/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.57 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26638944 | 0.84 | SOX18 (0.73) | SOX18CYP1A2HDAC1HDAC8 | |
| SCHEMBL21530605 | 0.83 | BID (0.79) | SOX18KAT8EP300KAT5BID | |
| SCHEMBL20332766 | 0.82 | SOX18 (0.70) | SOX18KAT8EP300KAT5CYP1A2 | |
| SCHEMBL20332761 | 0.82 | SOX18 (0.70) | SOX18KAT8EP300KAT5CYP1A2 | |
| SCHEMBL26638875 | 0.82 | SOX18 (0.69) | SOX18KAT8EP300KAT5BID | |
| SCHEMBL26744430 | 0.82 | SOX18 (0.69) | SOX18KAT8EP300KAT5BID | |
| SCHEMBL574679 | 0.80 | KAT8 (0.69) | SOX18KAT8EP300KAT5BID | |
| SCHEMBL20332765 | 0.80 | SOX18 (0.67) | SOX18CYP1A2 | |
| SCHEMBL26745727 | 0.78 | SOX18 (0.63) | SOX18CYP1A2PDPK1PTGER4PTGER2 | |
| SCHEMBL20771694 | 0.73 | KAT8 (1.00) | SOX18KAT8EP300KAT5BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355557-A1 | ANTIVIRAL SOX INHIBITORS | GERTRUDE BIOMEDICAL PTY LTD (AU) | 2023-11-09 | — | — | US | disclosed |
| US-20230355557-A1 | ANTIVIRAL SOX INHIBITORS | GERTRUDE BIOMEDICAL PTY LTD (AU) | 2023-11-09 | — | — | US | disclosed |
| US-20230355557-A1 | ANTIVIRAL SOX INHIBITORS | GERTRUDE BIOMEDICAL PTY LTD (AU) | 2023-11-09 | — | — | US | disclosed |
| WO-2022040719-A1 | ANTIVIRAL SOX INHIBITORS | GERTRUDE BIOMEDICAL PTY LTD (AU) | 2022-03-03 | — | — | WO | disclosed |
| US-20190337880-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS-AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2019-11-07 | — | — | US | disclosed |
| WO-2018112545-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS- AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2018-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337880-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS-AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | SOX18, PROX1, RUNX1 | SOX18 1/4885KAT8 1226/4885EP300 680/4885 |
| US-20230355557-A1 | ANTIVIRAL SOX INHIBITORS | SOX18, IRF3, YBX1 | SOX18 1/4885KAT8 780/4885EP300 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.