SCHEMBL574679

SCHEMBL574679

O=C(O)c1c(O)cccc1CCc1ccc(O)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 3/20 0.69
EP300 Q09472 2/20 0.69
KAT5 Q92993 2/20 0.69
SOX18 P35713 1/20 0.67
BID P55957 7/20 0.65
MCL1 Q07820 7/20 0.65
BCL2L1 Q07817 6/20 0.65
BAK1 Q16611 6/20 0.65
SAE1 Q9UBE0 2/20 0.56
PPARG P37231 1/20 0.56
PPARA Q07869 1/20 0.56
KAT2A Q92830 1/20 0.56
KAT2B Q92831 1/20 0.56
SGMS1 Q86VZ5 2/20 0.53
SGMS2 Q8NHU3 2/20 0.53
ACHE P22303 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21530605 0.90 BID (0.79) KAT8EP300KAT5SOX18BID
SCHEMBL20771694 0.82 KAT8 (1.00) KAT8EP300KAT5SOX18BID
SCHEMBL12249375 0.82 SOX18 (0.57) KAT8EP300KAT5SOX18BID
SCHEMBL20333017 0.80 SOX18 (1.00) KAT8EP300KAT5SOX18BID
SCHEMBL20781123 0.79 KAT8 (0.60) KAT8EP300KAT5SOX18BID
SCHEMBL22331059 0.79 KAT8 (0.60) KAT8EP300KAT5SOX18BID
SCHEMBL29919590 0.78 BID (0.67) KAT8EP300KAT5BIDMCL1
SCHEMBL3954149 0.78 BID (0.67) KAT8EP300KAT5BIDMCL1
SCHEMBL16870672 0.77 BID (0.61) KAT8EP300KAT5SOX18BID
SCHEMBL11868931 0.77 BID (0.61) KAT8EP300KAT5SOX18BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220273585-A1 Composition comprising at least one natural or synthetic non-euphoric cannabinoid and its method of manufacture TILMAN (BE) 2022-09-01 US claimed
EP-4049654-A1 COMPOSITION COMPRISING AT LEAST ONE NATURAL OR SYNTHETIC CANNABINOID WITHOUT EUPHORIC EFFECT AND MANUFACTURING METHOD THEREOF Eleonor (BE) 2022-08-31 EP claimed
EP-1311258-B1 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INC (US) 2005-04-06 EP claimed
EP-1311258-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS Insmed Incorporated (US) 2003-05-21 EP claimed
US-6541522-B2 Including longistyline A-2-carboxylic acid as a dietary supplement INSMED INCORPORATED 2003-04-01 US claimed
US-20020058708-A1 Compositions containing hypotriglyceridemically active stilbenoids SHAMAN PHARMACEUTICALS 2002-05-16 US claimed
US-20020055541-A1 Compositions containing hypotriglyceridemically active stilbenoids SHAMAN PHARMACEUTICALS, INC. 2002-05-09 US claimed
WO-2002013809-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO claimed
WO-2002013806-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO claimed
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS CARGILL, INCORPORATED (US) 2026-01-15 US disclosed
US-12458049-B2 Steviol glycoside solubility enhancers CARGILL, INCORPORATED (US) 2025-11-04 US disclosed
US-20250160327-A1 USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS ECOLE POLYTECHNIQUE (FR) 2025-05-22 US disclosed
EP-3952651-B1 USE OF BENZOXEPINE DERIVATIVES AS HERBICIDES ECOLE POLYTECH (FR) 2025-04-23 EP disclosed
US-12193443-B2 Use of benzoxepin derivatives as a herbicide ECOLE POLYTECHNIQUE (FR) 2025-01-14 US disclosed
US-20020055541-A1 Compositions containing hypotriglyceridemically active stilbenoids SHAMAN PHARMACEUTICALS, INC. 2002-05-09 US disclosed
WO-2002013809-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
WO-2002013806-A2 COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS INSMED INCORPORATED (US) 2002-02-21 WO disclosed
WO-2001074753-A1 SYNTHETIC DERIVATIVES OF LUNULARIC ACID, MEDICAMENTS CONTAINING SAID COMPOUNDS, METHOD FOR PRODUCING THE LUNULARIC ACID DERIVATIVES AND THE USE THEREOF Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2001-10-11 WO disclosed
WO-2001074753-A1 SYNTHETIC DERIVATIVES OF LUNULARIC ACID, MEDICAMENTS CONTAINING SAID COMPOUNDS, METHOD FOR PRODUCING THE LUNULARIC ACID DERIVATIVES AND THE USE THEREOF Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2001-10-11 WO disclosed
WO-1988000968-A2 PROCESS FOR INDUCING SECONDARY METABOLITE PRODUCTION IN PLANT CULTURES AND MEANS THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058708-A1 Compositions containing hypotriglyceridemically active stilbenoids CPT1B, CPT1A, LIPC KAT8 3259/4885EP300 1329/4885KAT5 2043/4885
US-20220273585-A1 Composition comprising at least one natural or synthetic non-euphoric cannabinoid and its method of manufacture CNR2, CNR1, FAAH KAT8 4854/4885EP300 4466/4885KAT5 4674/4885
US-12458049-B2 Steviol glycoside solubility enhancers SI, TAS2R7, TAS2R31 KAT8 2863/4885EP300 2581/4885KAT5 4310/4885
US-20260013535-A1 STEVIOL GLYCOSIDE SOLUBILITY ENHANCERS TAS2R7, TAS2R31, TAS2R40 KAT8 3626/4885EP300 2689/4885KAT5 4812/4885
US-20250160327-A1 USE OF CHROMENE OR CHROMANE DERIVATIVES AS HERBICIDAL AGENTS CBX8, CBX3, CDYL KAT8 739/4885EP300 4646/4885KAT5 2502/4885
US-20020055541-A1 Compositions containing hypotriglyceridemically active stilbenoids CPT1B, CPT1A, LIPC KAT8 3259/4885EP300 1329/4885KAT5 2043/4885
US-12193443-B2 Use of benzoxepin derivatives as a herbicide BROX, CYP4X1, DDT KAT8 4631/4885EP300 4641/4885KAT5 3012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.