Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2039364 | 0.85 | KCNK3 (0.44) | CYP2C19HPGDALDH1A1SMN1; SMN2KCNK3 | |
| Hydrochloric Acid SCHEMBL2035441 | 0.81 | CYP2C19 (0.46) | CYP2C19HPGDALDH1A1P2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL2040601 | 0.81 | CYP2C19 (0.43) | CYP2C19HPGDALDH1A1P2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL5856427 | 0.81 | CYP2C19 (0.43) | CYP2C19HPGDALDH1A1P2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL5853691 | 0.81 | CYP2C19 (0.43) | CYP2C19HPGDALDH1A1P2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL5852878 | 0.79 | CYP2C19 (0.41) | CYP2C19HPGDALDH1A1P2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL2036881 | 0.77 | HPGD (0.44) | CYP2C19HPGDALDH1A1P2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL2037710 | 0.76 | MEN1 (0.43) | HPGDALDH1A1KDM4ESMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL2036089 | 0.76 | HPGD (0.43) | CYP2C19HPGDALDH1A1SMN1; SMN2HDAC1 | |
| Hydrochloric Acid SCHEMBL5853355 | 0.76 | HPGD (0.43) | CYP2C19HPGDALDH1A1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701595-B2 | Process for producing novel synthetic basestocks | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-07-11 | — | — | US | disclosed |
| EP-2516598-B1 | PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS | EXXONMOBIL CHEM PATENTS INC (US) | 2016-06-29 | — | — | EP | disclosed |
| US-8530712-B2 | Process for producing novel synthetic basestocks | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-20130131410-A1 | Process for Producing Novel Synthetic Basestocks | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2516598-A2 | PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS | Exxonmobil Chemical Patents Inc. (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079042-A2 | PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110160502-A1 | Process for Producing Novel Synthetic Basestocks | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131410-A1 | Process for Producing Novel Synthetic Basestocks | PYM1, SCO2, SPIN4 | CYP2C19 4717/4885HPGD 4503/4885ALDH1A1 4882/4885 |
| US-20110160502-A1 | Process for Producing Novel Synthetic Basestocks | PYM1, SPIN4, SCO2 | CYP2C19 4731/4885HPGD 4535/4885ALDH1A1 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.