Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 11/20 | 0.38 |
| ▸ | ABL1 | P00519 | 9/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.38 |
| ▸ | PRKDC | P78527 | 5/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | HCK | P08631 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 4/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.38 |
| ▸ | RET | P07949 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20334938 | 0.89 | ADORA2A (0.38) | ADORA2AADORA1PI4KBADORA2BPI4KA | |
| SCHEMBL24499994 | 0.81 | LIMK1 (0.41) | ADORA2AADORA1PI4KBADORA2BPI4KA | |
| SCHEMBL20334667 | 0.78 | ADORA2A (0.41) | ADORA2AADORA1PI4KBADORA2BPI4KA | |
| SCHEMBL23960227 | 0.78 | ADORA2A (0.41) | ADORA2AADORA1PI4KBADORA2BPI4KA | |
| SCHEMBL6925165 | 0.73 | SRC (0.58) | PI4KBSRCABL1PIK3CDPIK3CA | |
| SCHEMBL23960265 | 0.72 | RET (0.36) | ADORA2AADORA1PI4KBSRCABL1 | |
| SCHEMBL409234 | 0.67 | ADORA2A (0.50) | ADORA2AADORA1PI4KBADORA2BPI4KA | |
| SCHEMBL756293 | 0.66 | ADORA2A (0.53) | ADORA2AADORA1PI4KBADORA2BPI4KA | |
| SCHEMBL459311 | 0.64 | LIMK1 (0.41) | ADORA2AADORA1PI4KBADORA2BPI4KA | |
| SCHEMBL13077902 | 0.64 | ADORA2A (0.51) | ADORA2AADORA1PI4KBADORA2BPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144843-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2022-05-12 | — | — | US | disclosed |
| US-20210332057-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2021-10-28 | — | — | US | disclosed |
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | PHARMASCIENCE INC. (CA) | 2018-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332057-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | BTK, LCK, SYK | ADORA2A 1602/4885ADORA1 759/4885PI4KB 705/4885 |
| US-20180179210-A1 | Inhibitors of the TEC Kinase Enzyme Family | TEC, BTK, LCK | ADORA2A 4885/4885ADORA1 4881/4885PI4KB 203/4885 |
| US-20220144843-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | BTK, LCK, SYK | ADORA2A 1602/4885ADORA1 759/4885PI4KB 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.