Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.41 |
| ▸ | RET | P07949 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 7/20 | 0.38 |
| ▸ | ABL1 | P00519 | 5/20 | 0.38 |
| ▸ | HCK | P08631 | 4/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.37 |
| ▸ | PI4KA | P42356 | 2/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20334656 | 0.78 | ADORA2A (0.42) | ADORA2AADORA1RETSRCABL1 | |
| SCHEMBL20334938 | 0.67 | ADORA2A (0.38) | ADORA2AADORA1RETSRCABL1 | |
| SCHEMBL20334667 | 0.66 | ADORA2A (0.41) | ADORA2AADORA1ADORA2BPI4KBPI4KA | |
| SCHEMBL1913702 | 0.65 | GAA (0.38) | RETPIK3CAMTOR | |
| SCHEMBL12323880 | 0.64 | ADORA2A (0.37) | ADORA2AADORA1RETADORA2BPI4KB | |
| SCHEMBL756293 | 0.64 | ADORA2A (0.53) | ADORA2AADORA1RETSRCABL1 | |
| SCHEMBL19733383 | 0.62 | ADORA2A (0.47) | ADORA2AADORA1ADORA2BPI4KBPI4KA | |
| SCHEMBL13077902 | 0.62 | ADORA2A (0.51) | ADORA2AADORA1RETSRCADORA2B | |
| SCHEMBL24499994 | 0.62 | LIMK1 (0.41) | ADORA2AADORA1SRCABL1HCK | |
| SCHEMBL18268598 | 0.62 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BPI4KBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332057-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332057-A1 | AMINONORBORNANE DERIVATIVE AND MANUFACTURE METHOD THEREFOR AND USE THEREOF | BTK, LCK, SYK | ADORA2A 1602/4885ADORA1 759/4885RET 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.