Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.37 |
| ▸ | PI4KA | P42356 | 4/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20334656 | 0.81 | ADORA2A (0.42) | LIMK1ADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL20334938 | 0.80 | ADORA2A (0.38) | LIMK1ADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL20334667 | 0.79 | ADORA2A (0.41) | LIMK1ADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL13593762 | 0.77 | LIMK1 (0.44) | LIMK1ADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL6924506 | 0.72 | PIK3CD (0.49) | PI4KAPI4K2BPI4K2API4KBPIK3CD | |
| SCHEMBL23239683 | 0.71 | ADORA1 (0.36) | LIMK1ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL24392169 | 0.69 | — | — | |
| SCHEMBL459311 | 0.69 | LIMK1 (0.41) | LIMK1ADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL21159362 | 0.67 | EGFR (0.42) | LIMK1ADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL19917018 | 0.67 | EGFR (0.42) | LIMK1ADORA2AADORA1ADORA2BPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | GALK1, PHKA1, PGK1 | LIMK1 79/4885ADORA2A 309/4885ADORA1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.