Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187377 | 0.73 | IDO1 (0.41) | AOC3IDO1TDO2ACHEDAO | |
| SCHEMBL10157213 | 0.70 | IDO1 (0.42) | AOC3IDO1TDO2TRPA1ACHE | |
| SCHEMBL10157190 | 0.70 | IDO1 (0.42) | AOC3IDO1TDO2TRPA1ACHE | |
| SCHEMBL10159881 | 0.70 | IDO1 (0.42) | AOC3IDO1TDO2TRPA1ACHE | |
| SCHEMBL12201672 | 0.70 | IDO1 (0.42) | AOC3IDO1TDO2TRPA1ACHE | |
| SCHEMBL25245356 | 0.70 | ALOX5 (0.30) | — | |
| SCHEMBL20336534 | 0.70 | ALOX5 (0.30) | — | |
| SCHEMBL12027408 | 0.69 | IDO1 (0.46) | AOC3IDO1TDO2MEN1KMT2A | |
| SCHEMBL7893366 | 0.69 | ESR1 (0.52) | AOC3IDO1TDO2TRPA1ACHE | |
| SCHEMBL84956 | 0.69 | IDO1 (0.46) | AOC3IDO1TDO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565410-B1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3565410-A1 | PICOLINAMIDES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2019-11-13 | — | — | EP | disclosed |
| US-10246417-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018129238-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018129237-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-12 | — | — | WO | disclosed |
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186743-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | AOC3 1260/4885IDO1 582/4885TDO2 720/4885 |
| US-10246417-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | AOC3 1260/4885IDO1 582/4885TDO2 720/4885 |
| US-20180186742-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | AOC3 1260/4885IDO1 582/4885TDO2 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.