Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12983948 | 0.84 | HTT (0.60) | HTTSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL27524897 | 0.82 | HTT (0.57) | HTTSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9815415 | 0.82 | HTT (0.51) | HTTSMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL9815425 | 0.78 | HTT (0.53) | HTTSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL31171014 | 0.78 | MAPT (0.54) | HTTSMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL11526803 | 0.78 | HTT (0.71) | HTTSMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL9479729 | 0.77 | BACE1 (0.48) | MAPTALDH1A1LMNAPOLBFBP1 | |
| SCHEMBL30434455 | 0.76 | KMT2A (0.50) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29833583 | 0.76 | HTT (0.60) | HTTSMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL359006 | 0.76 | HTT (0.64) | HTTSMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | claimed |
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | claimed |
| US-7956011-B2 | Materials and methods for the photodirected synthesis of oligonucleotide arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2011-06-07 | — | — | US | disclosed |
| US-20090270279-A1 | Materials and Methods for the Photodirected Synthesis of Oligonucleotide Arrays | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2009-10-29 | — | — | US | disclosed |
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | disclosed |