Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444661 | 0.87 | HTT (0.52) | MAPTALDH1A1HTTTHRBPOLB | |
| SCHEMBL8447846 | 0.86 | GSTP1 (0.57) | MAPTALDH1A1HTTTHRBPOLB | |
| SCHEMBL8445210 | 0.84 | HTT (0.55) | MAPTALDH1A1HTTTHRBPOLB | |
| SCHEMBL8444657 | 0.80 | HTT (0.58) | MAPTALDH1A1HTTTHRBPOLB | |
| SCHEMBL2033657 | 0.78 | HTT (0.53) | MAPTALDH1A1HTTPOLBSMN1; SMN2 | |
| SCHEMBL18261765 | 0.77 | THRB (0.61) | MAPTALDH1A1HTTTHRBPOLB | |
| SCHEMBL8444659 | 0.75 | HTT (0.53) | MAPTALDH1A1HTTTHRBPOLB | |
| SCHEMBL11526803 | 0.75 | HTT (0.71) | MAPTALDH1A1HTTPOLBL3MBTL1 | |
| SCHEMBL8941933 | 0.74 | ALDH1A1 (0.67) | MAPTALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL8447844 | 0.73 | HTT (0.51) | MAPTALDH1A1HTTTHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709425-A1 | LINKER COMPOUNDS AND LIGAND-DRUG CONJUGATES, PREPARATION METHODS AND USES THEREOF | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. (CN) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024235105-A1 | LINKER COMPOUNDS AND LIGAND-DRUG CONJUGATES, PREPARATION METHODS AND USES THEREOF | BIOCYTOGEN PHARMACEUTICALS (BEIJING) CO., LTD. (CN) | 2024-11-21 | — | — | WO | disclosed |