Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115863 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1FAAHSMN1; SMN2 | |
| SCHEMBL242105 | 0.84 | MEN1 (0.46) | MEN1KMT2AALDH1A1FAAHSMN1; SMN2 | |
| SCHEMBL2116143 | 0.80 | MEN1 (0.45) | MEN1KMT2AALDH1A1FAAHMAPT | |
| SCHEMBL2135252 | 0.80 | MEN1 (0.45) | MEN1KMT2AALDH1A1FAAHMAPT | |
| SCHEMBL2135253 | 0.79 | MEN1 (0.43) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL2114350 | 0.79 | MEN1 (0.43) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL2113888 | 0.78 | FAAH (0.54) | MEN1KMT2AFAAHLMNAKDM4E | |
| SCHEMBL1965328 | 0.78 | FAAH (0.54) | MEN1KMT2AFAAHLMNAKDM4E | |
| SCHEMBL2114335 | 0.78 | MEN1 (0.49) | MEN1KMT2AALDH1A1FAAHLMNA | |
| SCHEMBL2114333 | 0.78 | MEN1 (0.49) | MEN1KMT2AALDH1A1FAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180185319-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING DIMETHYL FUMARATE | BIOGEN MA INC. | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185319-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING DIMETHYL FUMARATE | FH, FAH, MGMT | MEN1 414/4885KMT2A 297/4885ALDH1A1 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.