Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281451 | 0.83 | LMNA (0.36) | WDR5TP53ALDH1A1LMNAHPGD | |
| SCHEMBL20337611 | 0.83 | KHK (0.34) | WDR5TP53ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL20337635 | 0.80 | LMNA (0.34) | WDR5TP53ALDH1A1LMNAHPGD | |
| SCHEMBL20337795 | 0.75 | ALDH1A1 (0.37) | WDR5ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL20337721 | 0.73 | RPS6KA5 (0.37) | WDR5ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL20337612 | 0.73 | RPS6KA5 (0.37) | WDR5ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL20337608 | 0.73 | POLB (0.36) | WDR5TP53ALDH1A1LMNAHPGD | |
| SCHEMBL18281473 | 0.72 | SMPD3 (0.38) | WDR5ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL20337758 | 0.70 | HDAC3 (0.36) | WDR5ALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL20337686 | 0.70 | NR4A2 (0.47) | TP53ALDH1A1HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933049-B2 | Mobilizing agents and uses therefor | THE UNIVERSITY OF QUEENSLAND (AU) | 2021-03-02 | — | — | US | disclosed |
| US-20180185328-A1 | MOBILIZING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185328-A1 | MOBILIZING AGENTS AND USES THEREFOR | C3AR1, CSF3R, C5AR1 | WDR5 2932/4885TP53 2107/4885ALDH1A1 2492/4885 |
| US-10933049-B2 | Mobilizing agents and uses therefor | C3AR1, CSF3R, C5AR1 | WDR5 2932/4885TP53 2107/4885ALDH1A1 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.