SCHEMBL20339019

SCHEMBL20339019

COc1ccc(N(c2ccc(OC)cc2)c2cc(OC)cc(OC)c2Cc2c(OC)cc(OC)cc2N(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CYP1A2 P05177 3/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
NPC1 O15118 1/20 0.37
APLNR P35414 1/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CYP1A1 P04798 2/20 0.36
CYP1B1 Q16678 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20354378 0.83 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL31257110 0.78 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL20339017 0.78 CA12 (0.38) CA12CA1CA2CA7CA9
SCHEMBL8944063 0.78 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL2096172 0.74 ALDH1A1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL8943675 0.74 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL21553432 0.73 ALDH1A1 (0.54) CYP1A2LMNATSHRNPC1NFE2L2
SCHEMBL8944319 0.72 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL17971147 0.70 CA1 (0.42) CA12CA1CA2CA7CA9
SCHEMBL8943802 0.70 PTGES (0.51) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562817-A1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS Centre National de la Recherche Scientifique (CNRS) (FR) 2019-11-06 EP disclosed
WO-2018122359-A1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2018-07-05 WO disclosed