SCHEMBL20339138

CC(C)c1cc(F)c(NS(=O)(=O)c2c[nH]c3cc(Cl)ccc23)nc1F.C[S+]([O-])c1c(Cl)ccc2c(S(=O)(=O)Nc3cc(F)c(Cl)cc3F)c[nH]c12

nearest known ligand 0.32

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	SGK1	O00141	4/20	0.32

▸	CCR2	P41597	2/20	0.31

▸	SLC40A1	Q9NP59	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30286430	0.82	CCR2 (0.37)	SGK1CCR2
SCHEMBL21545897	0.82	CCR2 (0.37)	SGK1CCR2
SCHEMBL21545871	0.82	CCR2 (0.37)	CCR2SLC40A1
SCHEMBL30286508	0.82	CCR2 (0.37)	CCR2SLC40A1
SCHEMBL20339166	0.81	SGK1 (0.38)	SGK1CCR2SLC40A1
SCHEMBL20339152	0.76	CCR2 (0.45)	SGK1CCR2SLC40A1
SCHEMBL20354864	0.75	TDO2 (0.39)	SGK1CCR2SLC40A1
SCHEMBL21545945	0.73	CCR2 (0.37)	CCR2
SCHEMBL30286423	0.73	CCR2 (0.37)	CCR2
SCHEMBL20339158	0.73	AXL (0.32)	SGK1SLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3562820-A1	(AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES	UCB Pharma GmbH (DE)	2019-11-06	—	—	EP	claimed
WO-2018122232-A1	(AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES	UCB PHARMA GMBH (DE)	2018-07-05	—	—	WO	claimed
EP-3562820-A1	(AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES	UCB Pharma GmbH (DE)	2019-11-06	—	—	EP	disclosed
WO-2018122232-A1	(AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES	UCB PHARMA GMBH (DE)	2018-07-05	—	—	WO	disclosed