SCHEMBL20339337

SCHEMBL20339337

COc1ccc(O)c(C=O)c1.[Pd]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.96
TRIM24 O15164 1/20 0.70
TYR P14679 1/20 0.70
TRIM33 Q9UPN9 1/20 0.70
ALDH1A1 P00352 2/20 0.56
GABRA3 P34903 1/20 0.55
GABRA2 P47869 1/20 0.55
GABRB2 P47870 1/20 0.55
CA2 P00918 4/20 0.50
CA1 P00915 3/20 0.50
BACE1 P56817 1/20 0.49
NPC1 O15118 1/20 0.49
POLB P06746 1/20 0.49
RAB9A P51151 1/20 0.49
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
RECQL P46063 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559365 0.98 ERN1 (1.00) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL120412 0.98 ERN1 (1.00) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL29673489 0.96 ERN1 (0.96) ERN1TRIM24TYRTRIM33ALDH1A1
Mequinol SCHEMBL11563732 0.91 ERN1 (0.86) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL8193524 0.85 ERN1 (0.76) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL31285081 0.85 ERN1 (0.77) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL28337239 0.85 TYR (0.96) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL19798735 0.84 ERN1 (0.74) ERN1TRIM24TYRTRIM33
SCHEMBL29399003 0.84 ERN1 (0.74) ERN1TRIM24TYRTRIM33
SCHEMBL133876 0.82 TYR (1.00) ERN1TRIM24TYRTRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562815-B1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF DELTA-LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2021-12-29 EP claimed
US-11179709-B2 Catalyst composition for a production process of δ-lactone from carbon dioxide and 1,3-butadiene PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2021-11-23 US claimed
CN-110506041-A Carbon monoxide-olefin polymeric for the manufacturing method by carbon dioxide and 1,3- butadiene manufacture delta-lactone PTT GLOBAL CHEMICAL PUBLIC CO LTD 2019-11-26 CN claimed
EP-3562815-A1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF - LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT Global Chemical Public Company Limited (TH) 2019-11-06 EP claimed
US-20190321813-A1 CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF delta-LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2019-10-24 US claimed
WO-2018124978-A1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF δ- LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2018-07-05 WO claimed
EP-3562815-B1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF DELTA-LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2021-12-29 EP disclosed
US-11179709-B2 Catalyst composition for a production process of δ-lactone from carbon dioxide and 1,3-butadiene PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2021-11-23 US disclosed
CN-110506041-A Carbon monoxide-olefin polymeric for the manufacturing method by carbon dioxide and 1,3- butadiene manufacture delta-lactone PTT GLOBAL CHEMICAL PUBLIC CO LTD 2019-11-26 CN disclosed
EP-3562815-A1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF - LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT Global Chemical Public Company Limited (TH) 2019-11-06 EP disclosed
US-20190321813-A1 CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF delta-LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2019-10-24 US disclosed
WO-2018124978-A1 A CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF δ- LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2018-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11179709-B2 Catalyst composition for a production process of δ-lactone from carbon dioxide and 1,3-butadiene CTNND1, DHCR24, DEGS1 ERN1 1686/4885TRIM24 3641/4885TYR 926/4885
US-20190321813-A1 CATALYST COMPOSITION FOR A PRODUCTION PROCESS OF delta-LACTONE FROM CARBON DIOXIDE AND 1,3-BUTADIENE CTNND1, DHCR24, LBR ERN1 1663/4885TRIM24 3458/4885TYR 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.