Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 16/20 | 0.74 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399003 | 1.00 | ERN1 (0.74) | ERN1TRIM24TYRTRIM33HDAC4 | |
| SCHEMBL13209706 | 0.88 | ERN1 (0.67) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL120412 | 0.85 | ERN1 (1.00) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL29559365 | 0.85 | ERN1 (1.00) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL1639484 | 0.85 | ERN1 (0.68) | ERN1TRIM24TYRTRIM33HDAC4 | |
| SCHEMBL20339337 | 0.84 | ERN1 (0.96) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL29673489 | 0.84 | ERN1 (0.96) | ERN1TRIM24TYRTRIM33 | |
| SCHEMBL24086095 | 0.83 | ERN1 (0.74) | ERN1 | |
| SCHEMBL29682880 | 0.83 | ERN1 (0.74) | ERN1 | |
| SCHEMBL6642692 | 0.83 | ERN1 (0.60) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | DIC CORPORATION (JP) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022716-A1 | POLYMERIZABLE COMPOUND AND OPTICAL ISOMER | SMC4, MAP1LC3C, ZW10 | ERN1 2084/4885TRIM24 1527/4885TYR 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.