Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.84 |
| ▸ | CTSB | P07858 | 5/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.84 |
| ▸ | NPC1 | O15118 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.69 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.66 |
| ▸ | APP | P05067 | 1/20 | 0.65 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340332 | 1.00 | CTSL (0.84) | CTSLCTSBTDP1NPC1MAPT | |
| Echinatin SCHEMBL7193984 | 0.91 | CTSL (1.00) | CTSLCTSBTDP1CYP1A1CYP1B1 | |
| Echinatin SCHEMBL618086 | 0.91 | CTSL (1.00) | CTSLCTSBTDP1CYP1A1CYP1B1 | |
| Echinatin SCHEMBL29466900 | 0.91 | CTSL (1.00) | CTSLCTSBTDP1CYP1A1CYP1B1 | |
| SCHEMBL26113846 | 0.87 | CTSB (0.86) | CTSLCTSBTDP1NPC1MAPT | |
| SCHEMBL7188106 | 0.86 | MAPT (1.00) | TDP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL7188111 | 0.86 | MAPT (1.00) | TDP1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL20563578 | 0.85 | CTSL (0.75) | CTSLCTSBTDP1NPC1MAPT | |
| SCHEMBL29395318 | 0.85 | CTSL (0.75) | CTSLCTSBTDP1NPC1MAPT | |
| SCHEMBL1723179 | 0.83 | MAPT (1.00) | CTSLCTSBNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562803-A1 | NOTCH INHIBITORS FOR USE IN THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA | Università degli Studi di Roma "La Sapienza" (IT) | 2019-11-06 | — | — | EP | claimed |
| WO-2018122689-A1 | NOTCH INHIBITORS FOR USE IN THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA | UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" (IT) | 2018-07-05 | — | — | WO | claimed |
| CN-111683986-B | Composition for forming cured film, alignment material, and retardation material | 日产化学株式会社 | 2025-01-10 | — | — | CN | disclosed |
| CN-119053661-A | Composition for forming cured film, alignment material, and retardation material | 日产化学株式会社 | 2024-11-29 | — | — | CN | disclosed |
| CN-119053888-A | Resin composition for thermosetting photo-alignment film | 日产化学株式会社 | 2024-11-29 | — | — | CN | disclosed |
| CN-106905278-B | A method of 5 kinds of separation preparation has antiinflammatory active compound from falcate crazyweed herb | 中国科学院西北高原生物研究所 | 2019-08-23 | — | — | CN | disclosed |