SCHEMBL20341448

SCHEMBL20341448

CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2ccc(CC(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)cc21

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GSTP1 P09211 1/20 0.49
▸ ALB P02768 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ USP2 O75604 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ FOLH1 Q04609 16/20 0.46
▸ NAALAD2 Q9Y3Q0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145803 0.89 MEN1 (0.49) GSTP1ALBMEN1USP2ALDH1A1
SCHEMBL22895225 0.85 ALB (0.46) GSTP1ALBMEN1USP2ALDH1A1
SCHEMBL14729474 0.75 LMNA (0.57) GSTP1ALBMEN1USP2ALDH1A1
SCHEMBL23192497 0.73 ALB (0.51) GSTP1ALBMEN1MAPTHTT
SCHEMBL23192580 0.73 ALB (0.51) GSTP1ALBMEN1MAPTHTT
SCHEMBL31658980 0.72 MAPT (0.80) GSTP1MEN1USP2ALDH1A1LMNA
SCHEMBL19089912 0.71 FOLH1 (0.65) FOLH1
SCHEMBL24910527 0.71 NAALAD2 (0.66) ALBFOLH1NAALAD2
SCHEMBL19719052 0.70 FTO (0.52) GSTP1ALBMEN1ALDH1A1MAPT
SCHEMBL19360806 0.70 FOLH1 (0.70) FOLH1NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 GSTP1 1051/4885ALB 1023/4885MEN1 59/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 GSTP1 1051/4885ALB 1023/4885MEN1 59/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 GSTP1 1051/4885ALB 1023/4885MEN1 59/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 GSTP1 1051/4885ALB 1023/4885MEN1 59/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 GSTP1 1051/4885ALB 1023/4885MEN1 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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