Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13207675 | 0.81 | LMNA (0.36) | — | |
| SCHEMBL26864406 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TDP1ANPEPENPEP | |
| SCHEMBL27009129 | 0.81 | CRAT (0.39) | ALDH1A1TDP1 | |
| SCHEMBL13207677 | 0.79 | TDP1 (0.35) | TDP1 | |
| SCHEMBL20342209 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TDP1ANPEPENPEP | |
| SCHEMBL16301558 | 0.75 | — | — | |
| SCHEMBL25626714 | 0.75 | — | — | |
| SCHEMBL13207698 | 0.74 | — | — | |
| SCHEMBL13937718 | 0.73 | — | — | |
| SCHEMBL12118194 | 0.73 | ANPEP (0.42) | ALDH1A1TDP1ANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |