Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26864406 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL10000224 | 0.79 | MGAM (0.46) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL20342166 | 0.74 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL12118194 | 0.74 | ANPEP (0.42) | ALDH1A1TDP1 | |
| SCHEMBL24115265 | 0.72 | ALDH1A1 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL25626714 | 0.72 | — | — | |
| SCHEMBL26864847 | 0.71 | ALDH1A1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL26864716 | 0.71 | ALDH1A1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL20342140 | 0.71 | ALDH1A1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL26864491 | 0.71 | ALDH1A1 (0.37) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |