Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285646 | 0.82 | HDAC1 (0.35) | PDE10AHDAC1 | |
| SCHEMBL10143645 | 0.78 | PDE10A (0.38) | PDE10AHDAC1 | |
| SCHEMBL18789807 | 0.77 | HDAC1 (0.35) | PDE10AHDAC1 | |
| SCHEMBL20162086 | 0.72 | HDAC1 (0.35) | PDE10AHDAC1 | |
| SCHEMBL17626629 | 0.72 | SUV39H2 (0.44) | PDE10AHDAC1 | |
| SCHEMBL12343964 | 0.69 | PDE8B (0.35) | PDE10AHDAC1 | |
| SCHEMBL12341046 | 0.69 | PDE10A (0.33) | PDE10AHDAC1 | |
| SCHEMBL25124896 | 0.64 | PDE10A (0.35) | PDE10A | |
| SCHEMBL12402544 | 0.64 | PDE10A (0.35) | PDE10AHDAC1 | |
| SCHEMBL25044484 | 0.64 | PDE8B (0.39) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145930-B1 | FUSED TRIAZOLE DERIVATIVES AS PHOSPHODIESTERASE 10A INHIBITORS | Celon Pharma Sa (PL) | 2018-07-04 | — | — | EP | disclosed |