Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17794409 | 0.88 | ELANE (0.47) | ELANEKMT2AATMMRGPRX4ACHE | |
| SCHEMBL17355719 | 0.87 | ELANE (0.47) | ELANEKMT2AATMACHETDP1 | |
| SCHEMBL9575341 | 0.87 | MRGPRX4 (0.42) | ELANEKMT2AMRGPRX4ACHEHDAC1 | |
| SCHEMBL12636054 | 0.86 | ELANE (0.50) | ELANEKMT2AATMTDP1POLB | |
| SCHEMBL9607783 | 0.85 | ELANE (0.49) | ELANEKMT2AATMTDP1POLB | |
| SCHEMBL17304967 | 0.84 | ELANE (0.43) | ELANEKMT2AATMACHETDP1 | |
| SCHEMBL23795424 | 0.84 | ELANE (0.51) | ELANEKMT2AATMACHETDP1 | |
| SCHEMBL30692737 | 0.84 | ELANE (0.51) | ELANEKMT2AATMACHETDP1 | |
| SCHEMBL26045249 | 0.84 | AKR1C3 (0.47) | ELANEKMT2AATMACHE | |
| SCHEMBL32667335 | 0.83 | ELANE (0.47) | ELANEKMT2AATMTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331965-B1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-05 | — | — | EP | disclosed |
| EP-3130650-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-07-04 | — | — | EP | disclosed |