Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980333 | 0.89 | SLC6A2 (0.36) | — | |
| SCHEMBL19980315 | 0.81 | TYR (0.39) | TYR | |
| SCHEMBL21156884 | 0.72 | ALOX5 (0.33) | — | |
| SCHEMBL23188990 | 0.67 | TSHR (0.38) | SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL23189041 | 0.66 | — | — | |
| SCHEMBL23259114 | 0.64 | NR3C2 (0.39) | LMNAXBP1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL14137736 | 0.64 | SLC6A4 (0.43) | LMNAXBP1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL19980070 | 0.64 | OR51E2 (0.41) | SMN1; SMN2 | |
| SCHEMBL20344484 | 0.63 | RXFP1 (0.36) | LMNANPSR1 | |
| SCHEMBL25732383 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342771-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2018-07-04 | — | — | EP | disclosed |