SCHEMBL2034464

SCHEMBL2034464

CCCC(O)C(C)=C(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41
HRH1 P35367 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GPR84 Q9NQS5 7/20 0.39
FFAR1 O14842 2/20 0.39
THRB P10828 1/20 0.36
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
PGGT1B P53609 1/20 0.36
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1781775 0.84 CHRM1 (0.37) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1781776 0.84 CHRM1 (0.37) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL6333528 0.84 CHRM1 (0.35) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL57044 0.82 OR51E2 (0.33) GPR84FFAR1
SCHEMBL56521 0.78 GPR84 (0.36) GPR84FFAR1THRBFNTAFNTB
SCHEMBL3693624 0.77 GPR84 (0.35) GPR84FFAR1
SCHEMBL57947 0.77 GPR84 (0.39) GPR84FFAR1FFAR4
SCHEMBL8604370 0.77 HTR2A (0.31) HTR2AHRH1
SCHEMBL1470450 0.76 OR51E2 (0.48) TDP1THRBFNTAFNTBPGGT1B
SCHEMBL11037365 0.76 MAPT (0.41) CHRM1AKR1A1CHRM3HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1867734-A Temporary wet strength additives PROCTER & GAMBLE (US) 2006-11-22 CN claimed
EP-1680546-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2006-07-19 EP claimed
WO-2005038132-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2005-04-28 WO claimed
US-20050082024-A1 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY 2005-04-21 US claimed
US-20050082023-A1 Temporary wet strength resins THE PROCTER & GAMBLE COMPANY 2005-04-21 US claimed
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 EP disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 US disclosed
EP-3004050-A1 CYANOSTILBENES Rolic AG (CH) 2016-04-13 EP disclosed
US-20160083655-A1 CYANOSTILBENES ROLIC AG (CH) 2016-03-24 US disclosed
WO-2014191292-A1 CYANOSTILBENES ROLIC AG (CH) 2014-12-04 WO disclosed
US-7959990-B2 Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light ROLIC AG (CH) 2011-06-14 US disclosed
EP-1676004-B1 FIBROUS STRUCTURES EXHIBITING IMPROVED WET STRENGTH PROPERTIES PROCTER & GAMBLE (US) 2010-11-17 EP disclosed
US-7125469-B2 Temporary wet strength resins THE PROCTER & GAMBLE COMPANY (US) 2006-10-24 US disclosed
EP-1680546-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2006-07-19 EP disclosed
EP-1676004-A2 FIBROUS STRUCTURES EXHIBITING IMPROVED WET STRENGTH PROPERTIES THE PROCTER & GAMBLE COMPANY (US) 2006-07-05 EP disclosed
WO-2005038132-A2 TEMPORARY WET STRENGTH ADDITIVES THE PROCTER & GAMBLE COMPANY (US) 2005-04-28 WO disclosed
WO-2005038131-A2 FIBROUS STRUCTURES EXHIBITING IMPROVED WET STRENGTH PROPERTIES THE PROCTER & GAMBLE COMPANY (US) 2005-04-28 WO disclosed
US-20050082026-A1 Fibrous structures exhibiting improved wet strength properties PROCTER & GAMBLE COMPANY, THE 2005-04-21 US disclosed
US-20050082024-A1 Temporary wet strength additives THE PROCTER & GAMBLE COMPANY 2005-04-21 US disclosed
US-20050082023-A1 Temporary wet strength resins THE PROCTER & GAMBLE COMPANY 2005-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083655-A1 CYANOSTILBENES LATS1, LATS2, CRY1 CHRM1 1444/4885AKR1A1 3775/4885CHRM3 967/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 CHRM1 1444/4885AKR1A1 3775/4885CHRM3 967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.