Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.45 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668739 | 0.83 | NPC1 (0.67) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL29784242 | 0.83 | NPC1 (0.67) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL21157003 | 0.81 | KMT2A (0.52) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL203644 | 0.81 | PARP1 (0.56) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL5729029 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL1092605 | 0.81 | MAOB (0.59) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL24653904 | 0.81 | KAT6A (0.50) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL9739886 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL27294341 | 0.80 | ADRB2 (0.62) | ALDH1A1KAT6AKDM4ENPC1RAB9A | |
| SCHEMBL23748267 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KAT6AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342771-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2018-07-04 | — | — | EP | disclosed |