Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | FSHR | P23945 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20344747 | 0.81 | BRD4 (0.42) | BRD4CREBBPDRD2ALOX5EPHX2 | |
| SCHEMBL20616463 | 0.76 | BRD4 (0.40) | BRD4MLNR | |
| SCHEMBL20616478 | 0.75 | BRD4 (0.37) | BRD4KDM4EMAPTPGR | |
| SCHEMBL20616476 | 0.75 | BRD4 (0.37) | BRD4CREBBPALOX5EPHX2BCL2 | |
| SCHEMBL20344751 | 0.71 | BRD4 (0.41) | BRD4CREBBPTRIM24TP53MAPT | |
| SCHEMBL20344802 | 0.69 | HDAC8 (0.34) | BRD4TP53MAPTPOLBFSHR | |
| SCHEMBL22756336 | 0.67 | ATAD2 (0.43) | BRD4DRD2DRD1DRD5MTNR1A | |
| SCHEMBL20344767 | 0.67 | BRD4 (0.37) | BRD4CREBBPALOX5EPHX2TRIM24 | |
| SCHEMBL15298954 | 0.67 | BRD4 (0.44) | BRD4CREBBPTRIM24TP53MAPT | |
| SCHEMBL20344739 | 0.67 | BRD4 (0.42) | BRD4CREBBPDRD2ALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |