Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23709485 | 0.82 | POLB (0.35) | ALOX15HSD17B10POLBNPC1ALDH1A1 | |
| SCHEMBL20186983 | 0.76 | FFAR4 (0.39) | ALOX15HSD17B10NPC1ALDH1A1KMT2A | |
| SCHEMBL22241441 | 0.68 | POLB (0.44) | POLBALDH1A1KMT2AHDAC1HDAC6 | |
| SCHEMBL24425765 | 0.67 | DAO (0.39) | POLBALDH1A1KMT2AHDAC1HDAC6 | |
| SCHEMBL18424069 | 0.67 | HPGD (0.50) | POLBKMT2AHPGDBRPF1MEN1 | |
| SCHEMBL20344777 | 0.66 | BRPF1 (0.50) | KMT2AHDAC8BRPF1HDAC1HDAC6 | |
| SCHEMBL20344772 | 0.66 | BRPF1 (0.42) | HSD17B10POLBNPC1KMT2AHDAC8 | |
| SCHEMBL20344802 | 0.65 | HDAC8 (0.34) | POLBKMT2AHDAC8BRPF1HDAC1 | |
| SCHEMBL20344751 | 0.65 | BRD4 (0.41) | POLBKMT2AHDAC8BRPF1HDAC1 | |
| SCHEMBL20616466 | 0.65 | BRD4 (0.36) | KMT2AHDAC8BRPF1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342766-A1 | SMALL MOLECULE COMPOUND FOR ENHANCING PLANT STRESS RESISTANCE | Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (CN) | 2018-07-04 | — | — | EP | disclosed |