SCHEMBL23709485

SCHEMBL23709485

C=NC(=O)N(CCC)c1ccc(NS(=O)(=O)Cc2ccc(C)c(F)c2)cc1C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.35
RORC P51449 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
BRPF1 P55201 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 1/20 0.32
P2RY12 Q9H244 1/20 0.32
KMT2A Q03164 3/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20344702 0.82 ALOX15 (0.36) POLBRORCHDAC8BRPF1HDAC1
SCHEMBL20186983 0.67 FFAR4 (0.39) RORCHDAC8BRPF1HDAC1HDAC6
SCHEMBL24425765 0.66 DAO (0.39) POLBHDAC1HDAC6ALDH1A1P2RY12
SCHEMBL18424069 0.66 HPGD (0.50) POLBBRPF1KMT2AMAPTMEN1
SCHEMBL20344772 0.65 BRPF1 (0.42) POLBHDAC8BRPF1HDAC1HDAC6
SCHEMBL20344777 0.65 BRPF1 (0.50) HDAC8BRPF1HDAC1HDAC6KMT2A
SCHEMBL20344802 0.64 HDAC8 (0.34) POLBRORCHDAC8BRPF1HDAC1
SCHEMBL20344751 0.64 BRD4 (0.41) POLBHDAC8BRPF1HDAC1HDAC6
SCHEMBL20616466 0.64 BRD4 (0.36) HDAC8BRPF1HDAC1HDAC6KMT2A
SCHEMBL20616467 0.64 BRD4 (0.39) HDAC8BRPF1HDAC1HDAC6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2021-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11076597-B2 High stress resistant plant growth regulator and preparation method and use thereof BOLA2; BOLA2B, MYB, PPA1 POLB 3031/4885RORC 2916/4885HDAC8 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.