Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 6/20 | 0.34 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18364987 | 1.00 | CLK1 (0.35) | CLK1NPC1RAB9AFABP4FABP3 | |
| SCHEMBL17029066 | 0.94 | P2RX3 (0.36) | FABP4FABP3NR1I2P2RX3 | |
| SCHEMBL17029065 | 0.94 | P2RX3 (0.36) | FABP4FABP3NR1I2P2RX3 | |
| SCHEMBL17039251 | 0.94 | P2RX3 (0.36) | FABP4FABP3NR1I2P2RX3 | |
| SCHEMBL17029018 | 0.92 | NR1I2 (0.40) | FABP4FABP3NR1I2 | |
| SCHEMBL18364988 | 0.83 | NR1I2 (0.36) | FABP4FABP3NR1I2P2RX3 | |
| SCHEMBL20344817 | 0.83 | NR1I2 (0.36) | FABP4FABP3NR1I2P2RX3 | |
| SCHEMBL17039255 | 0.83 | CLK1 (0.40) | CLK1NPC1RAB9AFABP4FABP3 | |
| SCHEMBL18364984 | 0.83 | NR1I2 (0.39) | FABP4FABP3NR1I2 | |
| SCHEMBL17039253 | 0.83 | NR1I2 (0.39) | FABP4FABP3NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107913-B1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2018-07-04 | — | — | EP | disclosed |