Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346812 | 0.92 | SIGMAR1 (0.41) | GPR88KDM4EGLATSHRL3MBTL1 | |
| SCHEMBL25949635 | 0.88 | USP2 (0.38) | GPR88KDM4EGLATSHRL3MBTL1 | |
| SCHEMBL18613070 | 0.86 | NPC1 (0.40) | GPR88KDM4EGLATSHRL3MBTL1 | |
| SCHEMBL19928692 | 0.84 | TSHR (0.37) | GPR88TSHRL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19227604 | 0.84 | NPC1 (0.42) | KDM4EGLATSHRL3MBTL1GAA | |
| SCHEMBL22857505 | 0.83 | TSHR (0.36) | GPR88TSHRGAAUSP2ALDH1A1 | |
| SCHEMBL22550830 | 0.83 | KDM4E (0.40) | KDM4EGLATSHRL3MBTL1GAA | |
| SCHEMBL24713588 | 0.82 | KDM4E (0.42) | GPR88KDM4EGLATSHRL3MBTL1 | |
| SCHEMBL22550677 | 0.82 | KDM4E (0.42) | GPR88KDM4EGLATSHRL3MBTL1 | |
| SCHEMBL178285 | 0.82 | KDM4E (0.42) | GPR88KDM4EGLATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548857-B2 | Biodegradable compound, lipid particle, composition comprising lipid particle, and kit | KABUSHIKI KAISHA TOSHIBA (JP) | 2023-01-10 | — | — | US | disclosed |
| US-11091476-B2 | Protein kinase inhibitors, preparation method and medical use thereof | GAN & LEE PHARMACEUTICALS | 2021-08-17 | — | — | US | disclosed |
| US-20200270217-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT | KABUSHIKI KAISHA TOSHIBA (JP) | 2020-08-27 | — | — | US | disclosed |
| US-20200165239-A1 | PROTEIN KINASE INHIBITORS, PREPARATION METHOD AND MEDICAL USE THEREOF | GAN & LEE PHARMACEUTICALS (CN) | 2020-05-28 | — | — | US | disclosed |
| EP-3342773-A1 | SYK INHIBITORS | Gilead Sciences, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091476-B2 | Protein kinase inhibitors, preparation method and medical use thereof | ROR1, DMPK, CDK9 | GPR88 759/4885KDM4E 1343/4885GLA 2778/4885 |
| US-20200165239-A1 | PROTEIN KINASE INHIBITORS, PREPARATION METHOD AND MEDICAL USE THEREOF | ROR1, DMPK, CDK9 | GPR88 759/4885KDM4E 1343/4885GLA 2778/4885 |
| US-11548857-B2 | Biodegradable compound, lipid particle, composition comprising lipid particle, and kit | KIT, NPY1R, CCKAR | GPR88 845/4885KDM4E 797/4885GLA 3183/4885 |
| US-20200270217-A1 | BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT | KIT, NPY1R, CCKAR | GPR88 845/4885KDM4E 797/4885GLA 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.